"Each application is expected to cost $1 million or more, and a…

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http://reason.com/blog/2016/05/05/fda-imposes-a-slow-motion-ban-on-e-cigar
"Each application is expected to cost $1 million or more, and a separate application will be required for each version of a product—an impossible burden for small businesses that sell vaporizers along with dozens of custom-made fluids."