---
title: ""MDMA (ecstasy) is an illicit drug causing long-term neurotoxicity.…"
date: 2019-10-04
source: facebook
type: Archer T. Ships shared a link.
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# "MDMA (ecstasy) is an illicit drug causing long-term neurotoxicity.…

*October 4, 2019 · Facebook*

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[https://www.sciencedirect.com/science/article/pii/S0161813X07001842](https://www.sciencedirect.com/science/article/pii/S0161813X07001842){target="_blank"}
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\"MDMA (ecstasy) is an illicit drug causing long-term neurotoxicity. Previous studies demonstrated the interaction of MDMA with alpha-7 nicotinic acetylcholine receptor (nAChR) in mouse brain membranes and the involvement of alpha-7 nicotinic acetylcholine receptors (nAChR) in dopaminergic neurotoxicity induced by MDMA in mice. The aim of the present study was to investigate the utility of memantine (MEM), an alpha-7 nAChR antagonist used for treatment of Alzheimer\'s disease patients, to prevent neurotoxicity induced by MDMA in rats and the oxidative effect of this amphetamine derivative in mice striatal synaptosomes.\"\
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[https://www.sciencedirect.com/science/article/pii/S0161813X07001842](https://www.sciencedirect.com/science/article/pii/S0161813X07001842){target="_blank"}
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