At best, we can say that current data (assuming it is truthfully...

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At best, we can say that current data (assuming it is truthfully reported) suggests that the Covid vaccine saved lives on net. But science is never "settled": https://en.wikipedia.org/wiki/Pancritical_rationalism 1. A huge percentage of scientific studies can't be reproduced: https://en.wikipedia.org/wiki/Replication_crisis 2. This is an observational study, not a prospective, controlled study. Health conscious, well-informed people might be more likely to be vaccinated and also have a higher baseline of health than people who are not vaccinated. 3. Scientists and government officials sometimes lie: https://www.science.org/content/article/research-misconduct-finding-neuroscientist-eliezer-masliah-papers-under-suspicion 4. As you point out, mRNA vaccines are new technology, and they might have introduced risks that we're not aware of yet. (See, for example, Vioxx, Thalidomide, and Fen/Phen for previous examples of medications that were later found to have deleterious side effects.) The behavior of the FDA/companies that make vaccines certainly doesn't inspire confidence: https://www.reuters.com/legal/government/wait-what-fda-wants-55-years-process-foia-request-over-vaccine-data-2021-11-18/